Serotonin Syndrome: Signs, Causes, and What to Do If It Happens
When your body gets too much serotonin, a natural chemical that helps regulate mood, sleep, and digestion. Also known as serotonin toxicity, it’s not a mental health issue—it’s a physical reaction that can turn life-threatening fast. This isn’t about feeling "too happy." It’s about your nervous system going into overdrive because too many drugs or supplements are pushing serotonin levels past safe limits.
It usually happens when you combine medications that boost serotonin. Think SSRIs, like fluoxetine or sertraline, commonly prescribed for depression and anxiety mixed with triptans, used for migraines, or even common OTC supplements like St. John’s wort. Even switching doses or starting a new drug can trigger it. The FDA has flagged over 200 drug combinations that carry this risk. You don’t need to be on multiple prescriptions—sometimes just one new addition is enough.
The signs come on fast. You might feel restless, shaky, or sweaty. Your heart races. Your muscles twitch or lock up. You could get a high fever, confusion, or even seizures. These aren’t side effects you can ignore. If you’re on antidepressants, migraine meds, painkillers like tramadol, or even certain cough syrups, and you suddenly feel off—don’t wait. Go to the ER. Early treatment stops it from becoming deadly.
What you’ll find in the posts below isn’t theory. It’s real-world cases, drug interaction warnings, and clear steps to protect yourself. From how generic drugs can carry hidden risks to why some people react worse than others, these articles give you the facts you need before your next prescription change. No guesswork. Just what works—and what could hurt you.
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St. John’s Wort and SSRIs: The Hidden Danger of Serotonin Syndrome
St. John’s Wort may seem like a safe natural remedy for depression, but combining it with SSRIs can trigger serotonin syndrome - a life-threatening condition. Learn the risks, symptoms, and what to do instead.
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