When it comes to treating erectile dysfunction, Avanafil, a fast-acting PDE5 inhibitor used to improve blood flow for erections. Also known as Stendra, it's one of the newer options on the market, designed to work quicker than older drugs like Viagra. Unlike some alternatives that take an hour or more to kick in, Avanafil can start working in as little as 15 minutes for many men. That’s not just convenient—it can make a real difference in spontaneity and confidence.
So how does it compare to the big names? Viagra (sildenafil), the original ED pill, takes about 30 to 60 minutes to work and lasts up to 4 to 5 hours. Cialis (tadalafil), on the other hand, lasts up to 36 hours, making it popular for men who want flexibility over several days. Avanafil sits between them: faster than Viagra, shorter than Cialis, but often with fewer side effects like facial flushing or upset stomach. Studies show fewer men stop taking Avanafil because of side effects compared to sildenafil.
It’s not just about timing. Dosing matters too. Avanafil comes in 50mg, 100mg, and 200mg strengths, with most starting at 100mg. You can take it with or without food—unlike Viagra, which loses effectiveness after a heavy meal. And while Cialis has a daily low-dose option, Avanafil is strictly taken as needed. That makes it a solid pick for men who don’t want to take medication every day but still need reliable, fast results.
What about cost? Generic Avanafil isn’t widely available yet, so brand-name Stendra can be pricier than generic sildenafil or tadalafil. But if you’ve tried other ED meds and they didn’t work well—or gave you too many side effects—Avanafil might be the missing piece. It’s not for everyone, but for those who need speed and fewer digestive issues, it’s a strong contender.
Below, you’ll find real comparisons between Avanafil and other ED treatments, including how they perform in practice, what users report, and which factors actually make one better than another for specific lifestyles. Whether you’re weighing options for the first time or switching after disappointment, these guides cut through the noise and show you what really works.
In‑depth look at Avanafil, how it stacks up against sildenafil, tadalafil, vardenafil and other ED options, with practical guidance on choosing the right treatment.
Medications